The US Department of Agriculture (USDA) has ordered the recall of 143m lb (64.9m kg) of beef - the largest meat recall in the country's history.
The recalled products come from a California meat plant, which officials say broke rules on cattle inspections.
However, the department says the health hazard is minimal. Much of the meat was purchased for school lunch and other federal nutrition programmes.
The plant is also being investigated over alleged animal cruelty.
Caution
The USDA recalled frozen beef products from the Westland/Hallmark Meat Co, dating back to 1 February 2006.
The move surpasses a 1999 recall of 35m lbs of ready-to-eat meats, officials said.
Some of the beef was destined for federal welfare assistance programmes, as well as some major fast-food chains.
But officials said most of the recalled meat has probably already been eaten.
The USDA described the recall as Class 2 - meaning there is a remote probability that the product could harm health if consumed.
"We don't know how much product is out there right now. We don't think there is a health hazard, but we do have to take this action," Dick Raymond, USDA undersecretary for food safety, told AP news agency.
Downer
The recall was ordered after department officials said the plant did not consistently order inspections of cattle which lost the ability to walk prior to slaughter.
Such "downer" cattle are at greater risk of contamination by E. coli, salmonella or contracting mad cow disease, as they have weaker immune systems and greater contact with faeces than walking cattle.
They should either be removed from the food supply, or receive a more thorough inspection following slaughter, officials say.
Operations at the plant had already been suspended after an undercover video shot by the Humane Society of America came to light.
The video appeared to show crippled and ill animals being prodded with the blades of a forklift truck, kicked, given electric shocks and sprayed with high-pressure water hoses by staff.
Two former employees were charged with animal cruelty on Friday, and the investigation continues.
The company says it has now taken action to ensure all employees handle animals humanely.
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